Wednesday September 12, 2007
Diamox (acetazolamide) - an antiepileptic !


Do you know that Diamox was originally introduced as an antiepileptic drug in 1952. It has been used to treat a variety of seizure types, including generalized tonic clonic, absence, and as add-on therapy for partial seizures! Acetazolamide's property of inhibiting carbonic anhydrase appears to retard abnormal, paroxysmal, excessive discharge from central nervous system neurons.

Diamox has been described as an effective drug of choice for catamenial epilepsy (epilepsy related to the menstrual cycle).


Reference:

1. Diamox - rxlist.com
2. Diamox - epilepsyfoundation.org
3. Acetazolamide in Women with Catamenial Epilepsy , Epilepsia, Volume 42, Number 6, June 2001 , pp. 746-749(4)