Thursday September 13, 2007
Effect of oxygen inhalation on heart !

No ! its not good to provide a lot of oxygen to patient. We are well aware of oxygen toxicity in lungs but oxygen also has negative ionotropic effect on heart and may reduce the cardiac output. Its important to wean FiO2 as tolerated to provide 'optimum' oxygenation.


Reference:

1. The effect of normobaric hyperoxia on cardiac index in healthy awake volunteers - Anaesthesia, Volume 58 Issue 9 Page 885-888, September 2003